Purified Anti-Human CD105 Antibody[SN6], Functional Grade (E-AB-F13100)
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For research use only.
| Alternate Names | HHT, RP11 228B, Osler Rendu Weber syndrome, END, HHT1, ORW1, CD105, ENG, endoglin, AI528660, AI662476, CD 105, CD105 antigen, EGLN, FLJ41744, ORW, Osler Rendu Weber syndrome 1, RP11 228B15.2, S-endoglin, SN6, AI528660, AI662476, CD 105, CD105, CD105 antigen, EGLN, END, Endoglin, Eng, FLJ41744, HHT1, ORW, ORW1, Osler Rendu Weber syndrome 1, RP11 228B15.2, S-endoglin, SN6, ENG, END |
| Clone | |
| Leadtime | Inquire |
| Verified Samples | Verified Samples in FCM: U937 |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells);FA Reported in the literature |
| Background | Endoglin (CD105) is a 90 kDa type I transmembrane glycoprotein of the zona pellucida (ZP) family of proteins (1-3). Endoglin and Betaglycan/T beta RIII are type III receptors for TGF beta superfamily ligands, sharing 71% aa identity in the transmembrane (TM) and cytoplasmic domains. Endoglin is highly expressed on proliferating vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta, with lower amounts on hematopoietic, mesenchymal and neural crest stem cells, activated monocytes, and lymphoid and myeloid leukemic cells. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells. |
| Immunogen | Recombinant Human CD105 protein |
| Abbre | CD105 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse IgG1,κ |
| Isotype Control | Purified Mouse IgG1, κ Isotype Control[MOPC-21], Functional Grade |
| Applications |
FCM;FA
|
| Research Areas | Immunology;Stem Cells;Cancer;Cardiovascular |
| Concentration |
≥ 1 mg/mL
|
| Conjugation | None (AF/LE) |
| Storage Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
| Application References | Olivier Nolan-Stevaux, et al. PLoS One. 2012;7(12):e50920. |
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